Neuroleptic malignant-like syndrome induced by metoclopramide

Authors

  • Dr. M. Reza Samie

    Corresponding author
    1. Department of Neurology, State University of New York at Buffalo, Buffalo, New York, U.S.A.
    • Department of Neurology, State University of New York at Buffalo, Movement Disorder Clinic-Erie County Medical Center, 462 Grider Street, Buffalo, NY 14215, U.S.A.
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Abstract

A prompt recognition of neuroleptic malignant-like syndrome is essential because of its high morbidity and mortality. A similar condition is described associated with metoclopramide, an agent with dopamine receptorblocking properties. An increased index of suspicion for early diagnosis of this condition and adjustment of metoclopramide dosing in patients with renal failure are emphasized.

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