Article

Central motor conduction to hand and leg muscles in Huntington's disease

  1. Dr. V. Hömberg1,*,
  2. H. W. Lange2

Article first published online: 12 OCT 2004

DOI: 10.1002/mds.870050305

Issue

Movement Disorders

Movement Disorders

Volume 5, Issue 3, pages 214–218, 1990

Additional Information

How to Cite

Hömberg, V. and Lange, H. W. (1990), Central motor conduction to hand and leg muscles in Huntington's disease. Mov. Disord., 5: 214–218. doi: 10.1002/mds.870050305

Author Information

  1. 1

    Neurological Therapy Center and Department of Neurology, Heinrich Heine University, Dusseldorf, F.R.G.

  2. 2

    Department of Psychiatry, Heinrich Heine University, Dusseldorf, F.R.G.

*Neurological Therapy Center, Heinrich Heine University, Hohensandweg 37, D-4000 Duesseldorf 13, F.R.G.

Publication History

  1. Issue published online: 12 OCT 2004
  2. Article first published online: 12 OCT 2004

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Keywords:

  • Huntington's disease;
  • Corticospinal tract;
  • Electromagnetic stimulation

Abstract

Using electromagnetic stimulation of motor cortex and cervical or lumbar roots, central conduction times to the thenar and abductor hallucis muscles bilaterally were determined in a population of 32 patients with definite Huntington's disease (HD) and 14 subjects at risk. The HD patients showed a wide variety of different severity of choreatic movements, disease duration, and total disability. None of the stimulation parameters (latency after cortical stimulation, amplitude, threshold, or central conduction time) revealed statistically significant abnormalities compared with a normal control group as well as between patient subgroups. The data indicate that central motor conduction to upper and lower extremity muscles remains normal in Huntington's disease irrespective of the severity of the disorder.

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