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Keywords:

  • Domperidone;
  • Acute dystonia;
  • Polycystic ovary syndrome;
  • Hyperestrogenism

Abstract

The occurrence of acute dystonic reactions (ADRs) due to domperidone administration in two young women is reported. In both patients, a typical polycystic ovary (PCO) syndrome was found. The possibility that the relative hyperestrogenism typical of PCO syndrome acted as a facilitating factor for ADR is discussed.