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Keywords:

  • Estrogen;
  • Chorea gravidarum;
  • Hormone-induced chorea;
  • Vaginal creams containing estrogen;
  • Drug-induced chorea;
  • Neurologic complications of pregnancy

Abstract

Recurrent chorea is described in a 61-year-old woman who had had chorea gravidarum when she was younger. The recurrent chorea appeared to be induced by a topical vaginal cream that contained conjugated estrogen. This case is consistent with the existence of a recurrent syndrome of hormone-induced chorea. The effect of estrogen on the basal ganglia is complex and not fully understood.