An unusual cause of recurrent chorea

Authors

  • John N. Caviness,

    1. Lee Silverman Center for Parkinson's Disease and Movement Disorders, Mayo Clinic Scottsdale, Scottsdale, Arizona, U.S.A.
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  • Dr. Manfred D. Muenter

    Corresponding author
    1. Lee Silverman Center for Parkinson's Disease and Movement Disorders, Mayo Clinic Scottsdale, Scottsdale, Arizona, U.S.A.
    • Lee Silverman Center for Parkinson's Disease and Movement Disorders, 13400 East Shea Boulevard, Scottsdale, AZ 85259, U.S.A.
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Abstract

Recurrent chorea is described in a 61-year-old woman who had had chorea gravidarum when she was younger. The recurrent chorea appeared to be induced by a topical vaginal cream that contained conjugated estrogen. This case is consistent with the existence of a recurrent syndrome of hormone-induced chorea. The effect of estrogen on the basal ganglia is complex and not fully understood.

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