Reflex blepharospasm associated with bilateral basal ganglia lesion

Authors

  • R. Larumbe,

    1. Movement Disorders Unit and Clinical Neurophysiology Service, Department of Neurology and Neuroradiology Unit, Department of Radiology, Clinica Universitaria, University of Navarra Medical School, Pamplona, Spain
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  • J. Vaamonde,

    1. Movement Disorders Unit and Clinical Neurophysiology Service, Department of Neurology and Neuroradiology Unit, Department of Radiology, Clinica Universitaria, University of Navarra Medical School, Pamplona, Spain
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  • J. Artieda,

    1. Movement Disorders Unit and Clinical Neurophysiology Service, Department of Neurology and Neuroradiology Unit, Department of Radiology, Clinica Universitaria, University of Navarra Medical School, Pamplona, Spain
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  • J. L. Zubieta,

    1. Movement Disorders Unit and Clinical Neurophysiology Service, Department of Neurology and Neuroradiology Unit, Department of Radiology, Clinica Universitaria, University of Navarra Medical School, Pamplona, Spain
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  • Dr. J. A. Obeso

    Corresponding author
    1. Movement Disorders Unit and Clinical Neurophysiology Service, Department of Neurology and Neuroradiology Unit, Department of Radiology, Clinica Universitaria, University of Navarra Medical School, Pamplona, Spain
    • Department of Neurology, Clinica Universitaria, Apdo. 192, 31080 Pamplona, Spain
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Abstract

A patient with a bilateral striatal lesion secondary to anoxia presented reflex blepharospasm associated with parkinsonism and dystonia in the limbs. The blink reflex excitability curve was enhanced and the R-2 response prolonged as in patients with essential blepharospasm. The findings in this patient support the notion that blepharospasm may be secondary to basal ganglia dysfunction through abnormal facilitation of reticular formation neurons controlling facial nucleus motoneuron excitability.

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