Variable onset of adult inherited focal dystonia: A problem for genetic studies

Authors

  • S. Micheli,

    1. Sección de Enfermedades Extrapiramidales, Hospital de Clinicas, Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina
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  • M. Fernández-Pardal,

    1. Sección de Enfermedades Extrapiramidales, Hospital de Clinicas, Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina
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  • P. Quesada,

    1. Movement Disorders Unit, Department of Neurology, Clinica Universitaria, University of Navarra, Pamplona, Spain
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  • T. Brannan,

    1. Movement Disorders Unit, Department of Neurology, Clinica Universitaria, University of Navarra, Pamplona, Spain
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  • Dr. J. A. Obeso

    Corresponding author
    1. Movement Disorders Unit, Department of Neurology, Clinica Universitaria, University of Navarra, Pamplona, Spain
    • Clinica Universitaria, Departmento de Neurología, 31080 Pamplona, Spain
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Abstract

We present two families with adult-onset focal dystonias with marked variability in disease expression, discuss the clinical findings in relation to the literature, and comment on the difficulties in determining the pattern of inheritance.

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