Leuprolide acetate for exhibitionism in huntington's disease

Authors

  • Dr. Stuart S. Rich,

    Corresponding author
    1. Clinical Neuropsychiatry Service, Department of Psychiatry, University of Chicago, Chicago, Illinois, U.S.A.
    • Department of Psychiatry, Rhode Island Hospital, 593 Eddy Street, Providence, RI 02903, U.S.A.
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  • Fred Ovsiew

    1. Clinical Neuropsychiatry Service, Department of Psychiatry, University of Chicago, Chicago, Illinois, U.S.A.
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Abstract

We treated a patient with Huntington's disease and exhibitionism using leuprolide acetate (Lupron Depot, TAP Pharmaceuticals), a gonadotropin-releasing hormone agonist. The result was elimination of his deviant sexual behavior with few side effects. This regimen may be a safe and effective pharmacological treatment of the paraphilias. The occurrence of paraphilias in basal ganglia disorders is reviewed.

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