Clinical impairment of sequential finger movements in Parkinson's disease

Authors

  • Rocco Agostino MD,

    1. Dipartimento Scienze Neurologiche, Università di Roma “La Sapienza,” Viale Università, Rome, Italy; and Mediterranean Neurologic Institute Neuromed, Pozzilli (IS), Italy
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  • Alfredo Berardelli MD,

    Corresponding author
    1. Dipartimento Scienze Neurologiche, Università di Roma “La Sapienza,” Viale Università, Rome, Italy; and Mediterranean Neurologic Institute Neuromed, Pozzilli (IS), Italy
    • Dipartimento Scienze Neurologiche Viale Università 30, 00185 Rome, Italy===

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  • Antonio Currà MD,

    1. Dipartimento Scienze Neurologiche, Università di Roma “La Sapienza,” Viale Università, Rome, Italy; and Mediterranean Neurologic Institute Neuromed, Pozzilli (IS), Italy
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  • Neri Accornero MD,

    1. Dipartimento Scienze Neurologiche, Università di Roma “La Sapienza,” Viale Università, Rome, Italy; and Mediterranean Neurologic Institute Neuromed, Pozzilli (IS), Italy
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  • Mario Manfredi MD

    1. Dipartimento Scienze Neurologiche, Università di Roma “La Sapienza,” Viale Università, Rome, Italy; and Mediterranean Neurologic Institute Neuromed, Pozzilli (IS), Italy
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Abstract

A retrospective analysis was performed on the records of 33 off-therapy parkinsonian patients. We analyzed the clinical score of three sequential upper limb movements: finger tapping, hand opening and closing, and forearm pronation and supination. The records showed that nearly all patients had difficulty in performing all three motor tasks, but movement scores showed that they found the sequential finger-tapping task significantly more difficult than the other two tasks. We suggest that parkinsonian patients find individual finger movements more difficult to execute than gross hand movements because-owing to their abnormal basal ganglia output-they lack the finer cortical control and greater facilitation that the finger task demands.

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