Communication

Target Profile Prediction: Cross-Activation of Peroxisome Proliferator-Activated Receptor (PPAR) and Farnesoid X Receptor (FXR)

  1. Ramona Steri1,
  2. Petra Schneider2,
  3. Alexander Klenner3,
  4. Matthias Rupp 3,4,
  5. Jan M. Kriegl5,
  6. Manfred Schubert-Zsilavecz1,
  7. Gisbert Schneider 3,6

Article first published online: 19 FEB 2010

DOI: 10.1002/minf.200900009

Issue

Molecular Informatics

Molecular Informatics

Volume 29, Issue 4, pages 287–292, April 12, 2010

Additional Information

How to Cite

Steri, R., Schneider, P., Klenner, A., Rupp , M., Kriegl, J. M., Schubert-Zsilavecz, M. and Schneider , G. (2010), Target Profile Prediction: Cross-Activation of Peroxisome Proliferator-Activated Receptor (PPAR) and Farnesoid X Receptor (FXR). Molecular Informatics, 29: 287–292. doi: 10.1002/minf.200900009

Author Information

  1. 1

    Institute of Pharmaceutical Chemistry, LIFF, ZAFES, Goethe-University, Max-von-Laue-Str. 9, 60438 Frankfurt a.M., Germany

  2. 2

    Schneider Consulting GbR, George-C.-Marshall Ring 33, 61440 Oberursel, Germany

  3. 3

    Chair for Chem- and Bioinformatics, Goethe-University, LIFF, Siesmayerstr. 70, 60323 Frankfurt a.M., Germany

  4. 4

    Helmholtz Zentrum München, Deutsches Forschungszentrum für Gesundheit und Umwelt, Ingolstädter Landstraße 1, 85764 Neuherberg, Germany

  5. 5

    Boehringer-Ingelheim Pharma, Department of Lead Discovery, 88397 Biberach, Germany

  6. 6

    Institute of Pharmaceutical Sciences, ETH Zürich, Wolfgang-Pauli-Str. 10, 8093 Zürich, Switzerland

Publication History

  1. Issue published online: 23 APR 2010
  2. Article first published online: 19 FEB 2010
  3. Manuscript Accepted: 15 JAN 2010
  4. Manuscript Received: 16 AUG 2009

Funded by

  • Frankfurt International Research Graduate School for Translational Biomedicine (FIRST)
  • Else-Kroener-Fresenius-Stiftung
  • LOEWE Lipid Signaling Forschungszentrum Frankfurt (LiFF)

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Keywords:

  • Lipid signaling;
  • Nuclear hormone receptor;
  • Pharmacophore;
  • Drug design;
  • Virtual screening

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