Review

Associating Drugs, Targets and Clinical Outcomes into an Integrated Network Affords a New Platform for Computer-Aided Drug Repurposing

  1. Tudor I. Oprea1,2,3,*,
  2. Sonny Kim Nielsen2,
  3. Oleg Ursu1,3,
  4. Jeremy J. Yang1,3,
  5. Olivier Taboureau2,
  6. Stephen L. Mathias1,3,
  7. Irene Kouskoumvekaki2,
  8. Larry A. Sklar3,
  9. Cristian G. Bologa1,3,*

Article first published online: 17 MAR 2011

DOI: 10.1002/minf.201100023

Issue

Molecular Informatics

Molecular Informatics

Special Issue: 18th European Symposium on Quantitative Structure-Activity Relationships (EuroQSAR 2010), September 19–24, 2010, Rhodes, Greece

Volume 30, Issue 2-3, pages 100–111, March 14, 2011

Additional Information

How to Cite

Oprea, T. I., Nielsen, S. K., Ursu, O., Yang, J. J., Taboureau, O., Mathias, S. L., Kouskoumvekaki, I., Sklar, L. A. and Bologa, C. G. (2011), Associating Drugs, Targets and Clinical Outcomes into an Integrated Network Affords a New Platform for Computer-Aided Drug Repurposing. Mol. Inf., 30: 100–111. doi: 10.1002/minf.201100023

Author Information

  1. 1

    Division of Biocomputing, Department of Biochemistry and Molecular Biology, University of New Mexico School of Medicine, MSC11 6145, Albuquerque, NM 87131, USA phone: +1 505 272 3694/6509; fax: +1 505 272 0238;

  2. 2

    Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Kemitorvet 8, Kgs. Lyngby, 2800, Denmark

  3. 3

    UNM Center for Molecular Discovery, University of New Mexico School of Medicine, MSC11 6145, Albuquerque, NM 87131, USA

*Division of Biocomputing, Department of Biochemistry and Molecular Biology, University of New Mexico School of Medicine, MSC11 6145, Albuquerque, NM 87131, USA phone: +1 505 272 3694/6509; fax: +1 505 272 0238;

Publication History

  1. Issue published online: 23 MAR 2011
  2. Article first published online: 17 MAR 2011
  3. Manuscript Accepted: 4 MAR 2011
  4. Manuscript Received: 21 FEB 2011

Funded by

  • NIH. Grant Numbers: 1R21GM095952-01, 5U54MH084690-03
  • Lundbeck Foundation. Grant Number: R32-A3932
  • Villum Foundation

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