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Keywords:

  • Food allergy;
  • Lipid transfer protein;
  • Oral allergy syndrome;
  • Panallergen;
  • Review;
  • Rosaceae fruits

Abstract

Lipid transfer proteins are widespread plant food allergens, highly resistant to food processing and to the gastrointestinal environment, which have recently been described as true food allergens in the Mediterranean area, where they have been associated with severe allergic reactions to foods in patients without pollen allergy. In this review we analyze their molecular structure, biological function, and clinical relevance in food allergy.