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Food & Function

Cocoa-rich diet prevents azoxymethane-induced colonic preneoplastic lesions in rats by restraining oxidative stress and cell proliferation and inducing apoptosis

  1. Ildefonso Rodríguez-Ramiro1,
  2. Sonia Ramos1,
  3. Elvira López-Oliva2,
  4. Angel Agis-Torres2,
  5. Miren Gómez-Juaristi1,
  6. Raquel Mateos1,
  7. Laura Bravo1,
  8. Luis Goya1,
  9. María Ángeles Martín1,3,*

Article first published online: 23 SEP 2011

DOI: 10.1002/mnfr.201100363

Issue

Molecular Nutrition & Food Research

Molecular Nutrition & Food Research

Volume 55, Issue 12, pages 1895–1899, December 2011

Additional Information

How to Cite

Rodríguez-Ramiro, I., Ramos, S., López-Oliva, E., Agis-Torres, A., Gómez-Juaristi, M., Mateos, R., Bravo, L., Goya, L. and Martín, M. Á. (2011), Cocoa-rich diet prevents azoxymethane-induced colonic preneoplastic lesions in rats by restraining oxidative stress and cell proliferation and inducing apoptosis. Mol. Nutr. Food Res., 55: 1895–1899. doi: 10.1002/mnfr.201100363

Author Information

  1. 1

    Instituto de Ciencia y Tecnología de Alimentos y Nutrición (ICTAN-CSIC), Madrid, Spain

  2. 2

    Facultad de Farmacia, Universidad Complutense de Madrid, Madrid, Spain

  3. 3

    CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), ISCIII, Madrid, Spain

*Instituto de Ciencia y Tecnología de Alimentos y Nutrición (ICTAN-CSIC), José Antonio Novais 10, Ciudad Universitaria, 28040, Madrid, Spain Fax: +34-91-549-36-27

Publication History

  1. Issue published online: 2 DEC 2011
  2. Article first published online: 23 SEP 2011
  3. Manuscript Accepted: 13 JUL 2011
  4. Manuscript Revised: 8 JUL 2011
  5. Manuscript Received: 30 MAY 2011

Funded by

  • Spanish Ministry of Science and Innovation (CICYT). Grant Numbers: AGL2007-64042/ALI, CSD 2007-00063
  • Consejo Superior de Investigaciones Científicas
  • Spanish Ministry of Science and Education

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  1. 1
    Maria Angeles Martin, Luis Goya, Sonia Ramos, Potential for preventive effects of cocoa and cocoa polyphenols in cancer, Food and Chemical Toxicology, 2013, 56, 336

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  2. 2
    Ildefonso Rodríguez-Ramiro, Sonia Ramos, Elvira López-Oliva, Angel Agis-Torres, Laura Bravo, Luis Goya, Maria Angeles Martín, Cocoa polyphenols prevent inflammation in the colon of azoxymethane-treated rats and in TNF-α-stimulated Caco-2 cells, British Journal of Nutrition, 2012, 1

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  3. 3
    Mostafa I. Waly, Amanat Ali, Nejib Guizani, Amani S. Al-Rawahi, Sardar A. Farooq, Mohammad S. Rahman, Pomegranate (Punica granatum) Peel Extract Efficacy as a Dietary Antioxidant against Azoxymethane-Induced Colon Cancer in Rat, Asian Pacific Journal of Cancer Prevention, 2012, 13, 8, 4051

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