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FilenameFormatSizeDescription
mnfr1740-sup-0001-figures1.doc460KFigure S1.
mnfr1740-sup-0002-figures2.doc335KFigure S2.
mnfr1740-sup-0003-tables1.doc31KTable S1. Analytical parameters for the HPLC–DAD method to analyze urolithin glucuronides and their aglycones: Rt (retention time), calibration curve, R2, linearity, limits of detection (LOD) and quantification (LOQ) and % of recovery.
mnfr1740-sup-0004-tables2.doc30KTable S2. Concentration (μM) of urolithins and their glucuronides in the culture medium of human aortic endothelial cells (HAECS) before and after treatment.
mnfr1740-sup-0005-tables3.doc63KTable S3. Profile of adhesion proteins expression in HAECs: TNF-α-treated cells (TNF-α) versus control cells (CT) and TNF-α + Uro-A glucuronide-treated cells (TNF-α + Uro-A-Gluc) versus TNF-α-treated cells. Cut-off value: up-regulation fold-change ≥ 1.3, down-regulation fold-change < –1.3.
mnfr1740-sup-0006-tables4.doc92KTable S4. Profile of human growth factors expression in HAECs: TNF-α-treated cells (TNF-α) versus control cells (CT), TNF-α + Uro-A glucuronide-treated cells (TNF-α + Uro-A-Gluc) versus TNF-α-treated cells and TNF-α + Uro-A-treated cells (TNF-α + UroA) versus TNF-α-treated cells. Cut-off value: up-regulation fold-change ≥ 1.3, down-regulation fold-change < –1.3.

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