These authors contributed equally to this work.
Molecular mechanism of curcumin on the suppression of cholesterol accumulation in macrophage foam cells and atherosclerosis
Article first published online: 30 MAY 2012
© 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Molecular Nutrition & Food Research
Volume 56, Issue 5, pages 691–701, May 2012
How to Cite
Zhao, J.-F., Ching, L.-C., Huang, Y.-C., Chen, C.-Y., Chiang, A.-N., Kou, Y. R., Shyue, S.-K. and Lee, T.-S. (2012), Molecular mechanism of curcumin on the suppression of cholesterol accumulation in macrophage foam cells and atherosclerosis. Mol. Nutr. Food Res., 56: 691–701. doi: 10.1002/mnfr.201100735
- Issue published online: 30 MAY 2012
- Article first published online: 30 MAY 2012
- Manuscript Revised: 26 JAN 2012
- Manuscript Accepted: 26 JAN 2012
- Manuscript Received: 3 NOV 2011
- National Scientific Council. Grant Number: NSC-99-2320-B-010-017-MY3
- National Health Research Institutes. Grant Number: NHRI-EX100-9608SC
- Tsou's Foundation. Grant Number: VGHUST 99-P6-41, VGHUST 100-G7-4-4
- Yen Tjing Ling Medical Foundation. Grant Number: CI-99-15; CI-100-26
Disclaimer: Supplementary materials have been peer-reviewed but not copyedited.
Figure S1. NBD-cholesterol uptake is independent of SR-A in macrophages.
Figure S2. Treatment with curcumin has no effect on the protein expression of lipid metabolism-related genes in macrophages.
Figure S3. The secretion of apolipoprotein AI from macrophages.
Figure S4. Transfection with LXRα siRNA successfully reduces protein expression of LXRα in macrophages.
Figure S5. Curcumin decreases the turnover rate of ABCA1 protein.
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