Disclaimer: Supplementary materials have been peer-reviewed but not copyedited.


Figure S1. Validation of differentially expressed genes identified by microarrays using qRT-PCR mRNA quantification in aorta.

Figure S2. NF-κB network based on differentially expressed genes of the curcumin group.

Figure S3. Two-dimensional hierarchical clustering analysis of mRNAs profiles in HUVECs.

Figure S4. Effects of curcumin on atherosclerotic lesion size and aortic gene expression after a short-term diet.


Table S1. Formulation of experimental diets.

Table S2. List of forward and reverse primers.

Table S3. Plasma lipid levels and antioxidant capacity. Plasmatic cholesterol and triglycerol concentrations in apoE−/− mice after 16 weeks on diet supplemented with curcumin. Values are means ± SEM for 15 mice per group.

mnfr1793-sup-0003-s3.xls269KTable S4. List of differentially expressed genes in the aorta of apoE−/− mice fed a diet supplemented with 0.2% curcumin for 16 weeks.
mnfr1793-sup-0004-s4.doc202KTable S5. Functional enrichment analysis based on Gene Ontology (GO) biological process terms of differentially expressed genes in mice aorta using GOstat database (
mnfr1793-sup-0005-s5.doc142KTable S6. Genes regulated by curcumin classified by molecular pathways according to KEGG database (

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