As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors.

mnfr1934-sup-0001-FigureS1.jpg48KFigure S1. Disorder prediction and modelling of tertiary structure. A, The disorder profile plot shows a disorder tendency over 50% for each residue in the Man e 5 primary sequence using different software predictors. B, Electrostatic potential surfaces for Man e 5, where blue indicates positive residues and red negative residues.
mnfr1934-sup-0002-FigureS2.jpg23KFigure S2. IgE cross-inhibition using sera of Brazilian and Italian allergic patients in SPHIAa microarray. Self inhibition of Hev b 5 (left), inhibition of Hev b 5 by Man e 5 (centre) and inhibition of Hev b 5 by manioc extract (Man e, right).
mnfr1934-sup-0003-FigureS3.jpg45KFigure S3. Cross-inhibition ELISA using manioc and latex extracts. A decrease of IgE-binding to manioc and latex protein extracts was tested using sera of manioc sensitized/allergic patients (n = 7) after pre-incubation with manioc (M), latex B (LB) or latex C (LC) protein extracts. Mean values and standard error of mean are shown as bar and whiskers, respectively. Statistical evaluation was performed using the Student's t-test. ns, not significant
mnfr1934-sup-0004-s1.doc54KSupporting Information

Please note: Wiley Blackwell is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.