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FilenameFormatSizeDescription
mnfr1894-sup-0001-FigureS1.pptx1618KSupporting Information Figure S1. Glyceollins suppresses angiogenesis via VEGFR-2 but not VEGFR-1. (A) HUVECs were loaded into the upper chamber of transwells, and VEGF (20 ng/ml) or PlGF (50 ng/ml) was added to low chamber in the absence or presence of glyceollins (20 mM) for 16 h. Cells migrated to the membrane were quantitated. The images shown are representative photographs of endothelial migration. (B) HUVECs were loaded onto the Matrigel-coated plates and treated with VEGF (20 ng/ml) or PlGF (50 ng/ml) in the absence or presence of glyceollins (20 mM). Microphotographs were taken after 12 h. The tubes density was quantitated. *p<0.05 vs. control.

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