These authors contributed equally to this research and should be viewed as co-first authors.
Food & Function
In vivo effect of oat cereal β-glucan on metabolic indexes and satiety-related hormones in diet-induced obesity C57-Bl mice
Article first published online: 19 MAR 2013
© 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Molecular Nutrition & Food Research
Volume 57, Issue 7, pages 1291–1294, July 2013
How to Cite
Lin, N., Li, Y., Tang, L., Shi, J. and Chen, Y. (2013), In vivo effect of oat cereal β-glucan on metabolic indexes and satiety-related hormones in diet-induced obesity C57-Bl mice. Mol. Nutr. Food Res., 57: 1291–1294. doi: 10.1002/mnfr.201200695
- Issue published online: 1 JUL 2013
- Article first published online: 19 MAR 2013
- Manuscript Accepted: 25 JAN 2013
- Manuscript Revised: 4 JAN 2013
- Manuscript Received: 17 OCT 2012
- Diet-induced obesity;
This study explored the dose-dependent effect of oat cereal β-glucan on improving metabolic indexes of obesity mice. C57-Bl mice were randomized to chow diet (N) group and high fat diet group and other three doses of oat β-glucan groups (low β-glucan, medium β-glucan, and high β-glucan). Energy intake, glucose, lipids, and appetite related hormones were tested. Dose-dependent relation was observed on oat β-glucan doses and body weight change, average energy intake, total cholesterol, HDL cholesterol, plasma neural peptide Y, arcuate neural peptide Y mRNA, and arcuate neural peptide Y receptor 2 mRNA level. Oat β-glucan helped to increase plasma peptide Y-Y and intestine peptide Y-Y expression in obesity mice.