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FilenameFormatSizeDescription
mnfr2034-sup-0001-FigureS1.pptx11020KFigure 1. Effect of chocolates on kidney weight, morphology and function at week 20. (a) Kidney weight, (b) Morphology of the kidney (PAS staining) (n = 8), (c) Kidney function (albuminuria), and (d) Immunohistochemistry of macrophage infiltrates (200x) (n = 5). Groups are abbreviated as: Mice fed control diet without cholesterol (CO, n = 19); mice fed control diet (i.e. with 1% cholesterol) (CC, n = 19); mice fed control diet supplemented with choc A (CCA, n = 19) and mice fed control diet supplemented with choc B (CCB, n = 19).
mnfr2034-sup-0002-TableS1.docx41KTable 1. Composition of the chocolate diets used in this study.
mnfr2034-sup-0003-TableS2.docx37K

Table 2A. Optimized SRM conditions for the analyses of the studied phenolic compounds by HPLC–MS/MS.

Table 2B. Optimized SRM conditions for the analyses of the selected metabolites by HPLC–MS/MS.

mnfr2034-sup-0004-TableS3.docx35KTable 3. Quantification of chocolate plasma metabolites (values expressed as nM in the plasma sample)
mnfr2034-sup-0005-TableS4.docx309KTable 4. Dietary composition of basic atherogenic diet without cholesterol

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