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Supporting Figure S1. Characterization of the differentiation state of C2C12 myotubes before 1,25(OH)2D3 treatment.

Supporting Figure S2. Cellular morphology of 5-day differentiated C2C12 myotubes treated with 0 or 10 nM 1,25(OH)2D3 for 72 hours.

Supporting Figure S3. Representative western blot showing the level of phosphorylated and total proteins involved in the translation initiation and elongation steps in C2C12 myotubes stimulated or not with insulin + leucine and treated or not with 10 nM 1,25(OH)2D3 .

Supporting Figure S4. Representative western blot showing the level of Insulin Receptor (IR) and Vitamin D Receptor (VDR) proteins in C2C12 myotubes treated or not with 10 nM 1,25(OH)2D3

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