Food & Function
Effects of single dose and regular intake of green tea (Camellia sinensis) on DNA damage, DNA repair, and heme oxygenase-1 expression in a randomized controlled human supplementation study
Article first published online: 28 FEB 2014
© 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Molecular Nutrition & Food Research
Volume 58, Issue 6, pages 1379–1383, June 2014
How to Cite
Ho, C. K., Choi, S.-w., Siu, P. M. and Benzie, I. F. F. (2014), Effects of single dose and regular intake of green tea (Camellia sinensis) on DNA damage, DNA repair, and heme oxygenase-1 expression in a randomized controlled human supplementation study. Mol. Nutr. Food Res., 58: 1379–1383. doi: 10.1002/mnfr.201300751
- Issue published online: 5 JUN 2014
- Article first published online: 28 FEB 2014
- Manuscript Accepted: 29 JAN 2014
- Manuscript Revised: 15 JAN 2014
- Manuscript Received: 11 OCT 2013
- The Hong Kong Polytechnic University
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Figure S1. Outline of the comet assay protocol
Table S1. Catechin concentration of the green tea used in the study, measured by liquid chromatography with tandem mass spectrometry (LC-MS/MS) as previously described in detail .
Table S2. Plasma catechins in samples collected pre- and post- single dose of green tea and after 7 days’ green tea supplementation, with water as control treatment; data are mean (SD) nmol/L, n = 16 (Table simplified from that previously published ).
Table S3. Primers for each gene of interest; primers were from Invitrogen (Life Technologies, Carlsbad, CA)
Table S4. Gene expression in peripheral lymphocytes collected from 16 healthy adults after a single dose and after 7-days’ supplementation with green tea or water (as control). Data are median (95% CIs) of ratio of the genes of interest with reference to two housekeeping genes, CD3ε and CD8β. Each sample was tested in triplicate.
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