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Table S1. Analytical parameters for the determination of urolithins in colon tissues, plasma and urine using UPLC-ESI-QTOF.

Table S2. Other possible occurring metabolites that were not detected in any sample after consuming pomegranate extracts.

Figure S1. Mean concentration of ellagic acid and urolithin metabolites in colon tissues (A, B), urine (C) and plasma (D). Results are expressed as mean±SEM. PE-1, pomegranate extract-1; PE-2, pomegranate extract-2.

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