M. A. Núñez-Sánchez and R. García-Villalba contributed equally to the work.
Targeted metabolic profiling of pomegranate polyphenols and urolithins in plasma, urine and colon tissues from colorectal cancer patients
Version of Record online: 16 FEB 2014
© 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Molecular Nutrition & Food Research
Volume 58, Issue 6, pages 1199–1211, June 2014
How to Cite
Nuñez-Sánchez, M. A., García-Villalba, R., Monedero-Saiz, T., García-Talavera, N. V., Gómez-Sánchez, M. B., Sánchez-Álvarez, C., García-Albert, A. M., Rodríguez-Gil, F. J., Ruiz-Marín, M., Pastor-Quirante, F. A., Martínez-Díaz, F., Yáñez-Gascón, M. J., González-Sarrías, A., Tomás-Barberán, F. A. and Espín, J. C. (2014), Targeted metabolic profiling of pomegranate polyphenols and urolithins in plasma, urine and colon tissues from colorectal cancer patients. Mol. Nutr. Food Res., 58: 1199–1211. doi: 10.1002/mnfr.201300931
- Issue online: 5 JUN 2014
- Version of Record online: 16 FEB 2014
- Manuscript Accepted: 16 JAN 2014
- Manuscript Revised: 14 JAN 2014
- Manuscript Received: 10 DEC 2013
- MINECO, Spain
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Table S1. Analytical parameters for the determination of urolithins in colon tissues, plasma and urine using UPLC-ESI-QTOF.
Table S2. Other possible occurring metabolites that were not detected in any sample after consuming pomegranate extracts.
Figure S1. Mean concentration of ellagic acid and urolithin metabolites in colon tissues (A, B), urine (C) and plasma (D). Results are expressed as mean±SEM. PE-1, pomegranate extract-1; PE-2, pomegranate extract-2.
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