Article

Identification of the b, d, and e analogs of vitamin B12 as monocarboxylic acids by 15N NMR spectroscopy

  1. Thomas J. Difeo1,
  2. Robert A. Schiksnis2,
  3. Rakesh K. Kohli1,
  4. Stanley J. Opella2,*,
  5. Amar Nath1,*

Article first published online: 13 APR 2005

DOI: 10.1002/mrc.1260270206

Issue

Magnetic Resonance in Chemistry

Magnetic Resonance in Chemistry

Volume 27, Issue 2, pages 127–129, February 1989

Additional Information

How to Cite

Difeo, T. J., Schiksnis, R. A., Kohli, R. K., Opella, S. J. and Nath, A. (1989), Identification of the b, d, and e analogs of vitamin B12 as monocarboxylic acids by 15N NMR spectroscopy. Magn. Reson. Chem., 27: 127–129. doi: 10.1002/mrc.1260270206

Author Information

  1. 1

    Department of Chemistry, Drexel University, Philadelphia, Pennsylvania 19104, USA

  2. 2

    Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA

*Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA

Publication History

  1. Issue published online: 13 APR 2005
  2. Article first published online: 13 APR 2005
  3. Manuscript Accepted: 15 AUG 1988
  4. Manuscript Received: 1 APR 1988

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Keywords:

  • 15N NMR;
  • Vitamin B12

Abstract

15N NMR spectra of b−, d−, and e-cyanocobalamin (vitamin B12) and the products of their amidation with 15N-labeled ammonia show that these analogs are monocarboxylic acids of vitamin B12 which result from hydrolysis at the respective propionamide groups.

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