1H and 31P NMR spectra of substituted methylphosphonic acids with indirect determination of 31P shifts

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Abstract

Proton and phosphorus magnetic resonance spectra of substituted methylphosphonic acids have been determined as a function of pH. A method has been developed for measuring the 31P shift indirectly by optimal heteronuclear decoupling of the 1H spectra of samples and standards. Control experiments have demonstrated the broad applicability of this technique to the characterization of low milligram samples of N-phosphonomethylglycine and potential metabolites.

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