Two new triterpenoid saponins from Pittosporum senacia Putterlick (Pittosporaceae)


Marie-Aleth Lacaille-Dubois, EA 4267, FDE/UFC, Laboratoire de Pharmacognosie, Faculté de Pharmacie, Université de Bourgogne, 7 bd. Jeanne D' Arc, BP 87900, 21079 Dijon cedex, France. E-mail:


From the branches of Pittosporum senacia Putterlick (Pittosporaceae), two new triterpenoid saponins, senaciapittosides A and B (1, 2), were isolated. Their structures were elucidated by extensive analysis of one- and two-dimensional nuclear magnetic resonance spectroscopy, high-resolution electrospray ionization mass spectrometry (HR-ESIMS) and chemical evidence as 3-O-[β-d-glucopyranosyl-(1 → 2)]-[α-l-arabinopyranosyl-(1 → 3)]-[α-l-arabinofuranosyl-(1 → 4)]-β-d-glucuronopyranosyl oleanolic acid 28-O-β-d-glucopyranosyl ester (1) and 3-O-[β-d-glucopyranosyl-(1 → 2)]-[α-l-arabinopyranosyl-(1 → 3)]-[α-l-arabinofuranosyl-(1 → 4)]-β-d-glucuronopyranosyl-22-O-α-l-arabinopyranosyl-21-acetoxy R1-barrigenol (2). Compound 2 presents an unusual glycosylation at C-22 of its aglycone. Copyright © 2012 John Wiley & Sons, Ltd.