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15N NMR of 1,4-dihydropyridine derivatives


Correspondence to: Inguna Goba, Physical Organic Chemistry, Latvian Institute of Organic Synthesis, 21 Aizkraukles St., Riga LV-1006, Latvia. E-mail:


In this article, we describe the characteristic 15N and 1HN NMR chemical shifts and 1J(15N–1H) coupling constants of various symmetrically and unsymmetrically substituted 1,4-dihydropyridine derivatives. The NMR chemical shifts and coupling constants are discussed in terms of their relationship to structural features such as character and position of the substituent in heterocycle, N-alkyl substitution, nitrogen lone pair delocalization within the conjugated system, and steric effects. Copyright © 2013 John Wiley & Sons, Ltd.