On T2-shortening by strongly magnetized spheres: A partial refocusing model
Article first published online: 23 JAN 2002
Copyright © 2002 Wiley-Liss, Inc.
Magnetic Resonance in Medicine
Volume 47, Issue 2, pages 257–263, February 2002
How to Cite
Gillis, P., Moiny, F. and Brooks, R. A. (2002), On T2-shortening by strongly magnetized spheres: A partial refocusing model. Magn Reson Med, 47: 257–263. doi: 10.1002/mrm.10059
- Issue published online: 23 JAN 2002
- Article first published online: 23 JAN 2002
- Manuscript Accepted: 4 OCT 2001
- Manuscript Revised: 3 OCT 2001
- Manuscript Received: 25 MAY 2001
- superparamagnetic particles
Computer simulations of water transverse relaxation induced by superparamagnetic particles are shown to disagree with the available theories, covering the slow diffusion domain. Understanding these new simulations, not in the slow diffusion domain, thus requires a new theoretical approach. A “partial refocusing model” is introduced for this purpose; it is based on a spatial division between an inner region where the gradients are too strong for the refocusing pulses to be efficient and an outer region where they are efficient. This model agrees with published simulations of relaxation induced by magnetic dipoles approximated as points. The validity domains of the various models are also compared. Magn Reson Med 47:257–263, 2002. © 2002 Wiley-Liss, Inc.