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Full Paper
Fast, pseudo-continuous arterial spin labeling for functional imaging using a two-coil system
Article first published online: 25 FEB 2004
DOI: 10.1002/mrm.10733
Copyright © 2004 Wiley-Liss, Inc.
1522-2594/asset/cover.gif?v=1&s=9512352d4133369aa19bc75e4ffa8001ea23b2d9 "Magnetic Resonance in Medicine")
Additional Information
How to Cite
Hernandez-Garcia, L., Lee, G. R., Vazquez, A. L. and Noll, D. C. (2004), Fast, pseudo-continuous arterial spin labeling for functional imaging using a two-coil system. Magnetic Resonance in Medicine, 51: 577–585. doi: 10.1002/mrm.10733
Publication History
- Issue published online: 25 FEB 2004
- Article first published online: 25 FEB 2004
- Manuscript Revised: 21 OCT 2003
- Manuscript Accepted: 21 OCT 2003
- Manuscript Received: 17 JUN 2003
Funded by
- University of Michigan (fMRI Laboratory and Center for Biomedical Engineering Research)
- Raynor Foundation
- Abstract
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Abstract
A fast, two-coil, pseudo-continuous labeling scheme is presented. This new scheme permits the collection of a multislice subtraction pair in <3 s, depending on the subject's arterial transit times. The method consists of acquiring both control and tag images immediately after a labeling period that matches the arterial transit time. The theoretical basis of the technique, and simulations of the signal during changes in both transit time and perfusion are presented. Experimental data from functional imaging experiments were collected to demonstrate the technique and its characteristics. Magn Reson Med 51:577–585, 2004. © 2004 Wiley-Liss, Inc.