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Full Paper
Accurate multislice gradient echo T1 measurement in the presence of non-ideal RF pulse shape and RF field nonuniformity
Article first published online: 16 APR 2001
DOI: 10.1002/mrm.1112
Copyright © 2001 Wiley-Liss, Inc.
1522-2594/asset/cover.gif?v=1&s=9512352d4133369aa19bc75e4ffa8001ea23b2d9 "Magnetic Resonance in Medicine")
Additional Information
How to Cite
Parker, G. J., Barker, G. J. and Tofts, P. S. (2001), Accurate multislice gradient echo T1 measurement in the presence of non-ideal RF pulse shape and RF field nonuniformity. Magnetic Resonance in Medicine, 45: 838–845. doi: 10.1002/mrm.1112
Publication History
- Issue published online: 16 APR 2001
- Article first published online: 16 APR 2001
- Manuscript Accepted: 17 NOV 2000
- Manuscript Revised: 27 SEP 2000
- Manuscript Received: 17 FEB 2000
Funded by
- Multiple Sclerosis Society of Great Britain and Northern Ireland
- Abstract
- Article
- References
- Cited By
Keywords:
- T1;
- RF nonuniformity;
- gradient echo;
- pulse profile
Abstract
A methodology is presented for estimating T1 using a two-point technique with a standard multislice gradient echo sequence. The method explicitly corrects for the shape of the RF pulse and for spatial variations in transmitted RF field intensity. Including these factors in the calculation of T1 gives a substantial improvement in accuracy and precision of two-point gradient echo T1 measurements in the presence of RF nonuniformity and non-ideal pulse profiles. The mean accuracy of the technique was found to be 1.4%. The mean precision was found to be 3.0%. The mean variation along the axis of a head coil was found to be 2.3%. Magn Reson Med 45:838–845, 2001. © 2001 Wiley-Liss, Inc.