Imaging anisotropic and viscous properties of breast tissue by magnetic resonance-elastography
Version of Record online: 27 JAN 2005
Copyright © 2005 Wiley-Liss, Inc.
Magnetic Resonance in Medicine
Volume 53, Issue 2, pages 372–387, February 2005
How to Cite
Sinkus, R., Tanter, M., Catheline, S., Lorenzen, J., Kuhl, C., Sondermann, E. and Fink, M. (2005), Imaging anisotropic and viscous properties of breast tissue by magnetic resonance-elastography. Magn Reson Med, 53: 372–387. doi: 10.1002/mrm.20355
- Issue online: 27 JAN 2005
- Version of Record online: 27 JAN 2005
- Manuscript Accepted: 10 SEP 2004
- Manuscript Revised: 9 SEP 2004
- Manuscript Received: 26 JAN 2004
- breast cancer;
MR-elastography is a new technique for assessing the viscoelastic properties of tissue. One current focus of elastography is the provision of new physical parameters for improving the specificity in breast cancer diagnosis. This analysis describes a technique to extend the reconstruction to anisotropic elastic properties in terms of a so-called transversely isotropic model. Viscosity is treated as being isotropic. The particular model chosen for the anisotropy is appealing because it is capable of describing elastic shear anisotropy of parallel fibers. The dependence of the reconstruction on the particular choice of Poisson's ratio is eliminated by extracting the compressional displacement contribution using the Helmholtz–Hodge decomposition. Results are presented for simulations, a polyvinyl alcohol breast phantom, excised beef muscle, and measurements in two patients with breast lesions (invasive ductal carcinoma and fibroadenoma). The results show enhanced anisotropic and viscous properties inside the lesions and an indication for preferred fiber orientation. Magn Reson Med 53:372–387, 2005. © 2005 Wiley-Liss, Inc.