Prostate spectroscopy at 3 Tesla using two-dimensional S-PRESS
Article first published online: 8 NOV 2006
Copyright © 2006 Wiley-Liss, Inc.
Magnetic Resonance in Medicine
Volume 56, Issue 6, pages 1220–1228, December 2006
How to Cite
Lange, T., Trabesinger, A. H., Schulte, R. F., Dydak, U. and Boesiger, P. (2006), Prostate spectroscopy at 3 Tesla using two-dimensional S-PRESS. Magn Reson Med, 56: 1220–1228. doi: 10.1002/mrm.21082
- Issue published online: 16 NOV 2006
- Article first published online: 8 NOV 2006
- Manuscript Accepted: 15 AUG 2006
- Manuscript Revised: 27 JUL 2006
- Manuscript Received: 12 JUN 2006
- ETH Zurich
- Philips Medical Systems
- strong coupling;
Two-dimensional (2D) strong-coupling point-resolved spectroscopy (S-PRESS) is introduced as a novel approach to 1H MR spectroscopy (MRS) in the prostate. The technique provides full spectral information and allows for an accurate characterization of the citrate (Cit) signal. The method is based on acquiring a series of PRESS spectra with constant total echo time (TE). The indirect dimension is encoded by varying the relative lengths of the first and second TEs (TE1 + TE2 = TE). In the resulting 2D spectra, only the signal of strongly coupled spin systems is spread into the second dimension, which leads to more clearly arranged spectra. Furthermore, the spectral parameters of Cit (coupling constant J and chemical shift difference δ of the AB spin system) can be determined with high accuracy in vivo. The sequence is analytically optimized for maximal “strong coupling peaks” of Cit at 3T. 2D S-PRESS spectra are compared with JPRESS spectra in vitro as well as in vivo. Magn Reson Med, 2006. © 2006 Wiley-Liss, Inc.