1522-2594/asset/MRM_left.gif?v=1&s=5969df2beb44a0574452410c77dd4f39f1258c50)
1522-2594/asset/MRM_right.gif?v=1&s=5393eec9f654b39630b945fd1b37ae8304304345)
Full Paper-Preclinical and Clinical Imaging
Max CAPR: High-resolution 3D contrast-enhanced MR angiography with acquisition times under 5 seconds
Article first published online: 16 AUG 2010
DOI: 10.1002/mrm.22434
Copyright © 2010 Wiley-Liss, Inc.
Additional Information
How to Cite
Haider, C. R., Borisch, E. A., Glockner, J. F., Mostardi, P. M., Rossman, P. J., Young, P. M. and Riederer, S. J. (2010), Max CAPR: High-resolution 3D contrast-enhanced MR angiography with acquisition times under 5 seconds. Magn. Reson. Med., 64: 1171–1181. doi: 10.1002/mrm.22434
Publication History
- Issue published online: 22 SEP 2010
- Article first published online: 16 AUG 2010
- Manuscript Accepted: 7 FEB 2010
- Manuscript Revised: 28 JAN 2010
- Manuscript Received: 25 SEP 2009
Keywords:
- contrast-enhanced MR angiography;
- 2D-SENSE;
- 2D-partial Fourier;
- temporal footprint;
- view sharing;
- single phase
Abstract
High temporal and spatial resolution is desired in imaging of vascular abnormalities having short arterial-to-venous transit times. Methods that exploit temporal correlation to reduce the observed frame time demonstrate temporal blurring, obfuscating bolus dynamics. Previously, a Cartesian acquisition with projection reconstruction-like (CAPR) sampling method has been demonstrated for three-dimensional contrast-enhanced angiographic imaging of the lower legs using two-dimensional sensitivity-encoding acceleration and partial Fourier acceleration, providing 1mm isotropic resolution of the calves, with 4.9-sec frame time and 17.6-sec temporal footprint. In this work, the CAPR acquisition is further undersampled to provide a net acceleration approaching 40 by eliminating all view sharing. The tradeoff of frame time and temporal footprint in view sharing is presented and characterized in phantom experiments. It is shown that the resultant 4.9-sec acquisition time, three-dimensional images sets have sufficient spatial and temporal resolution to clearly portray arterial and venous phases of contrast passage. It is further hypothesized that these short temporal footprint sequences provide diagnostic quality images. This is tested and shown in a series of nine contrast-enhanced MR angiography patient studies performed with the new method. Magn Reson Med, 2010. © 2010 Wiley-Liss, Inc.