Human imaging at 9.4 T using T2*-, phase-, and susceptibility-weighted contrast
Article first published online: 24 SEP 2010
Copyright © 2010 Wiley-Liss, Inc.
Magnetic Resonance in Medicine
Volume 65, Issue 2, pages 544–550, February 2011
How to Cite
Budde, J., Shajan, G., Hoffmann, J., Uğurbil, K. and Pohmann, R. (2011), Human imaging at 9.4 T using T2*-, phase-, and susceptibility-weighted contrast. Magn Reson Med, 65: 544–550. doi: 10.1002/mrm.22632
- Issue published online: 24 JAN 2011
- Article first published online: 24 SEP 2010
- Manuscript Accepted: 13 AUG 2010
- Manuscript Revised: 4 AUG 2010
- Manuscript Received: 4 MAR 2010
- phase images;
- susceptibility-weighted images;
- ultrahigh field
The effect of susceptibility differences on an MR image is known to increase with field strength. Magnetic field inhomogeneities within the voxels influence the apparent transverse relaxation time T2*, while effects due to different precession frequencies between voxels caused by local field variations are evident in the image phase, and susceptibility-weighted imaging highlights the veins and deep brain structures. Here, these three contrast mechanisms are examined at a field strength of 9.4 T. The T2* maps generated allow the identification of white matter structures not visible in conventional images. Phase images with in-plane resolutions down to 130 μm were obtained, showing high gray/white matter contrast and allowing the identification of internal cortical structures. The susceptibility-weighted images yield excellent visibility of small venous structures and attain an in-plane resolution of 175 μm. Magn Reson Med, 2011. © 2010 Wiley-Liss, Inc.