Model for the correction of motion-induced phase errors in multishot diffusion-weighted-MRI of the head: Are cardiac-motion-induced phase errors reproducible from beat-to-beat?
Article first published online: 28 DEC 2011
Copyright © 2011 Wiley Periodicals, Inc.
Magnetic Resonance in Medicine
Volume 68, Issue 2, pages 430–440, August 2012
How to Cite
O'Halloran, R. L., Holdsworth, S., Aksoy, M. and Bammer, R. (2012), Model for the correction of motion-induced phase errors in multishot diffusion-weighted-MRI of the head: Are cardiac-motion-induced phase errors reproducible from beat-to-beat?. Magn Reson Med, 68: 430–440. doi: 10.1002/mrm.23245
- Issue published online: 12 JUL 2012
- Article first published online: 28 DEC 2011
- Manuscript Accepted: 12 SEP 2011
- Manuscript Revised: 17 AUG 2011
- Manuscript Received: 30 JUN 2011
- Center of Advanced MR Technology at Stanford. Grant Numbers: P41RR09784, 1 R01 EB008706, 1 R01 EB008706 S1, 5 R01 EB002711, 1 R01 EB006526, 1 R21 EB006860
- Lucas Foundation
- Oak Foundation and GE Healthcare
- diffusion-weighted imaging
In diffusion-weighted imaging, multishot acquisitions are problematic due to intershot inconsistencies of the phase caused by motion during the diffusion-encoding gradients. A model for the motion-induced phase errors in diffusion-weighted-MRI of the brain is presented, in which rigid-body and nonrigid-body motion are separated. In the model, it is assumed that nonrigid-body motion is due to cardiac pulsation, and that the motion patterns are repeatable from beat-to-beat. To test the validity of this assumption, the repeatability of nonrigid-body motion-induced phase errors is quantified in three healthy volunteers. Nonrigid-body motion-induced phase was found to significantly correlate (P < 0.05) with pulse-oximeter waveforms in ∼83% of the pixels tested across all slices and subjects. Magn Reson Med, 2012. © 2011 Wiley Periodicals, Inc.