Resolution enhanced T1-insensitive steady-state imaging
Article first published online: 30 NOV 2011
Copyright © 2011 Wiley Periodicals, Inc.
Magnetic Resonance in Medicine
Volume 68, Issue 2, pages 421–429, August 2012
How to Cite
Derakhshan, J. J., Nour, S. G., Sunshine, J. L., Griswold, M. A. and Duerk, J. L. (2012), Resolution enhanced T1-insensitive steady-state imaging. Magn Reson Med, 68: 421–429. doi: 10.1002/mrm.23290
- Issue published online: 12 JUL 2012
- Article first published online: 30 NOV 2011
- Manuscript Accepted: 15 OCT 2011
- Manuscript Revised: 7 OCT 2011
- Manuscript Received: 7 MAR 2011
- National Heart, Lung, and Blood Institute. Grant Number: F30HL094002
- NIH. Grant Number: T32GM007250 (Case Western Reserve University Medical Scientist Training Program).
- rapid imaging;
- pulse sequence;
- T2 contrast;
- spatial resolution
Resolution enhanced T1-insensitive steady-state imaging (RE-TOSSI) is a new MRI pulse sequence for the generation of rapid T2 contrast with high spatial resolution. TOSSI provides T2 contrast by using nonequally spaced inversion pulses throughout a balanced steady-state free precession (SSFP) acquisition. In RE-TOSSI, these energy and time intensive adiabatic inversion pulses and associated magnetization preparation are removed from TOSSI after acquisition of the data around the center of k-space. Magnetization evolution simulations demonstrate T2 contrast in TOSSI as well as reduction in the widening of the point spread function width (by up to a factor of 4) to a near ideal case for RE-TOSSI. Phantom experimentation is used to characterize and compare the contrast and spatial resolution properties of TOSSI, RE-TOSSI, balanced SSFP, Half-Fourier Acquisition Single-Shot Turbo Spin Echo (HASTE), and turbo spin echo and to optimize the fraction of k-space acquired using TOSSI. Comparison images in the abdomen and brain demonstrate similar contrast and improved spatial resolution in RE-TOSSI compared with TOSSI; comparison balanced SSFP, HASTE, and turbo spin echo images are provided. RE-TOSSI is capable of providing high spatial resolution T2-weighted images in 1 s or less per image. Magn Reson Med, 2012. © 2011 Wiley Periodicals, Inc.