Regional variations of T2* in healthy and pathologic achilles tendon in vivo at 7 Tesla: Preliminary results

Authors

  • Vladimir Juras,

    Corresponding author
    1. Department of Radiology, Medical University of Vienna, High Field MR Center of Excellence, Vienna, Austria
    2. Department of Imaging Methods, Institute of Measurement Science, Bratislava, Slovakia
    • Department of Radiology, Medical University of Vienna, High Field MR Center of Excellence, Waeringer Guertel 18-20, Vienna A-1090, Austria

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  • Stefan Zbyn,

    1. Department of Radiology, Medical University of Vienna, High Field MR Center of Excellence, Vienna, Austria
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  • Christina Pressl,

    1. Department of Radiology, Medical University of Vienna, High Field MR Center of Excellence, Vienna, Austria
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  • Ladislav Valkovic,

    1. Department of Radiology, Medical University of Vienna, High Field MR Center of Excellence, Vienna, Austria
    2. Department of Imaging Methods, Institute of Measurement Science, Bratislava, Slovakia
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  • Pavol Szomolanyi,

    1. Department of Radiology, Medical University of Vienna, High Field MR Center of Excellence, Vienna, Austria
    2. Department of Imaging Methods, Institute of Measurement Science, Bratislava, Slovakia
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  • Ivan Frollo,

    1. Department of Imaging Methods, Institute of Measurement Science, Bratislava, Slovakia
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  • Siegfried Trattnig

    1. Department of Radiology, Medical University of Vienna, High Field MR Center of Excellence, Vienna, Austria
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Abstract

The aim of this study was to investigate Tinline image in the Achilles tendon (AT), in vivo, using a three-dimensional ultrashort time echo (3D-UTE) sequence, to compare field strength differences (3 and 7 T) and to evaluate a regional variation of Tinline image in healthy and pathologic tendon. Ten volunteers with no history of pain in the AT and five patients with chronic Achilles tendinopathy were recruited. 3D-UTE images were measured with the following echo times, at echo time = [0.07, 0.2, 0.33, 0.46, 0.59, 0.74, 1.0, 1.5, 2.0, 4.0, 6.0, and 9.0 ms]. Tinline image values in the AT were calculated by fitting the signal decay to biexponential function. Comparing volunteers between 3 and 7 T, short component Tinline image was 0.71 ± 0.17 ms and 0.34 ± 0.09 ms (P < 0.05); bulk long component Tinline image was 12.85 ± 1.87 ms and 10.28 ± 2.28 ms (P < 0.05). In patients at 7 T, bulk Tinline image was 0.53 ± 0.17 ms (P = 0.045, compared to volunteers), Tinline image was 11.49 ± 4.28 ms (P = 0.99, compared to volunteers). The results of this study suggest that the regional variability of AT can be quantified by Tinline image in in vivo conditions. Advanced quantitative imaging of the human AT using a 3D-UTE sequence may provide additional information to standard clinical imaging. Finally, as the preliminary patient data suggest, Tinline image may be a promising marker for the diagnosis of pathological changes in the AT. Magn Reson Med, 2012. © 2012 Wiley Periodicals, Inc.

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