Super-resolution methods in MRI: Can they improve the trade-off between resolution, signal-to-noise ratio, and acquisition time?
Article first published online: 1 FEB 2012
Copyright © 2012 Wiley Periodicals, Inc.
Magnetic Resonance in Medicine
Volume 68, Issue 6, pages 1983–1993, December 2012
How to Cite
Plenge, E., Poot, D. H. J., Bernsen, M., Kotek, G., Houston, G., Wielopolski, P., van der Weerd, L., Niessen, W. J. and Meijering, E. (2012), Super-resolution methods in MRI: Can they improve the trade-off between resolution, signal-to-noise ratio, and acquisition time?. Magn Reson Med, 68: 1983–1993. doi: 10.1002/mrm.24187
- Issue published online: 21 NOV 2012
- Article first published online: 1 FEB 2012
- Manuscript Accepted: 5 JAN 2012
- Manuscript Revised: 23 NOV 2011
- Manuscript Received: 28 JUL 2011
- Medical Delta (HST-Klein project), European Commission in the Seventh Framework Programme (ENCITE project)
- magnetic resonance imaging;
- image quality
Improving the resolution in magnetic resonance imaging comes at the cost of either lower signal-to-noise ratio, longer acquisition time or both. This study investigates whether so-called super-resolution reconstruction methods can increase the resolution in the slice selection direction and, as such, are a viable alternative to direct high-resolution acquisition in terms of the signal-to-noise ratio and acquisition time trade-offs. The performance of six super-resolution reconstruction methods and direct high-resolution acquisitions was compared with respect to these trade-offs. The methods are based on iterative back-projection, algebraic reconstruction, and regularized least squares. The algorithms were applied to low-resolution data sets within which the images were rotated relative to each other. Quantitative experiments involved a computational phantom and a physical phantom containing structures of known dimensions. To visually validate the quantitative evaluations, qualitative experiments were performed, in which images of three different subjects (a phantom, an ex vivo rat knee, and a postmortem mouse) were acquired with different magnetic resonance imaging scanners. The results show that super-resolution reconstruction can indeed improve the resolution, signal-to-noise ratio and acquisition time trade-offs compared with direct high-resolution acquisition. Magn Reson Med, 2012. © 2012 Wiley Periodicals, Inc.