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Due to a data processing error, the reported Q values in Figs. 3b and 5d and the Q parameter maps in Figs. 4 and 7 of the original manuscript were incorrect. The data processing error only affected the reported Q values in the original manuscript; all other results were not affected. The corrected Q plots and figures are provided below. The linear correlation between Q3/D and histological vessel density does not reach significance (R2 = 0.23, P = 0.06) (Fig. 3b). Representative Day 2 Q maps from one tumor in each treatment group are shown in Fig. 4. The change in Q (Fig. 5d) for the anti-VEGF group did not differ significantly from the changes observed in the control group (P = 0.06), although the anti-VEGF Day 2 Q estimates were significantly reduced relative to pre-treatment values (32 ± 4%, P < 0.0001) and relative to the control group at Day 2 (P < 0.005). The change in Q (Fig. 5d) for the anti-NRP1B group did not differ significantly from the changes observed in the control group (P = 0.42). Anti-NRP1B Day 2 Q estimates were significantly reduced relative to pre-treatment values (20 ± 6%, P < 0.05), but not relative to the control group at Day 2 (P = 0.10). Pre- and post-treatment Q parametric maps for the anti-VEGF group are shown in Fig. 7 (only the fourth row of the original figure is shown).

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Figure 3b. A one-to-one comparison of the mean Q3/D (with the assumption that D ∼ 1.0 μm2/ms) for viable tumor to the histological vessel density (number of vessels/viable tissue area) shows a linear correlation that does not reach significance (R2 = 0.23, P = 0.06).

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Figure 4. Representative Day 2 Q maps from one tumor in each treatment group.

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Figure 5d. Effects of anti-VEGF and anti-NRP1B treatment on the Q parameter: change from pre-treatment to 48 hours post-treatment.

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Figure 7. Representative Q maps from a single tumor treated with anti-VEGF, before treatment (left column) and 48 hours post-treatment (right column).

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