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Center-out echo-planar spectroscopic imaging with correction of gradient-echo phase and time shifts

Authors

  • Christian Labadie,

    1. Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany
    2. Université Claude Bernard, Laboratoire Spectrométrie Ionique et Moléculaire, Lyon, France
    3. University of Leipzig, Faculty of Physics and Earth Sciences, Leipzig, Germany
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  • Stefan Hetzer,

    1. Humboldt University, Bernstein Center for Computational Neuroscience, Berlin, Germany
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  • Jessica Schulz,

    1. Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany
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  • Toralf Mildner,

    1. Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany
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  • Monique Aubert-Frécon,

    1. Université Claude Bernard, Laboratoire Spectrométrie Ionique et Moléculaire, Lyon, France
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  • Harald E. Möller

    Corresponding author
    1. Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany
    2. University of Leipzig, Faculty of Physics and Earth Sciences, Leipzig, Germany
    • Max Planck Institute for Human Cognitive and Brain Sciences, Stephanstrasse 1a, D-04103 Leipzig, Germany
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Errata

This article is corrected by:

  1. Errata: Erratum to Center-out echo-planar spectroscopic imaging with correction of gradient-echo phase and time Shifts (Magn Reson Med 2013;70:16–24) Volume 74, Issue 5, 1502, Article first published online: 2 September 2015

Abstract

A procedure to prevent the formation of image and spectral Nyquist ghosts in echo-planar spectroscopic imaging is introduced. It is based on a novel Cartesian center-out echo-planar spectroscopic imaging trajectory, referred to as EPSICO, and combined with a correction of the gradient-echo phase and time shifts. Processing of homogenous sets of forward and reflected echoes is no longer necessary, resulting in an optimized spectral width. The proposed center-out trajectory passively prevents the formation of Nyquist ghosts by privileging the acquisition of the center k-space line with forward echoes at the beginning of an echo-planar spectroscopic imaging dwell time and by ensuring that all k-space lines and their respective complex conjugates are acquired at equal time intervals. With the proposed procedure, concentrations of N-acetyl aspartate, creatine, choline, glutamate, and myo-inositol were reliably determined in human white matter at 3 T. Magn Reson Med, 2013. © 2012 Wiley Periodicals, Inc.

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