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In vivo diffusion tensor MRI of the human heart: Reproducibility of breath-hold and navigator-based approaches

  1. Sonia Nielles-Vallespin1,2,*,
  2. Choukri Mekkaoui3,
  3. Peter Gatehouse1,2,
  4. Timothy G. Reese3,
  5. Jennifer Keegan1,2,
  6. Pedro F. Ferreira1,2,
  7. Steve Collins1,
  8. Peter Speier4,
  9. Thorsten Feiweier4,
  10. Ranil de Silva1,2,
  11. Marcel P. Jackowski5,
  12. Dudley J. Pennell1,2,
  13. David E. Sosnovik3,
  14. David Firmin1,2

Article first published online: 21 SEP 2012

DOI: 10.1002/mrm.24488

Additional Information

How to Cite

Nielles-Vallespin, S., Mekkaoui, C., Gatehouse, P., Reese, T. G., Keegan, J., Ferreira, P. F., Collins, S., Speier, P., Feiweier, T., de Silva, R., Jackowski, M. P., Pennell, D. J., Sosnovik, D. E. and Firmin, D. (2012), In vivo diffusion tensor MRI of the human heart: Reproducibility of breath-hold and navigator-based approaches. Magn Reson Med. doi: 10.1002/mrm.24488

Author Information

  1. 1

    Cardiovascular MR Unit, Royal Brompton And Harefield NHS Foundation Trust, London, UK

  2. 2

    Imperial College of Science, Technology and Medicine, London, UK

  3. 3

    Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA

  4. 4

    MR R&D, Siemens AG Healthcare Sector, Erlangen, Germany

  5. 5

    Institute of Mathematics and Statistics, University of São Paulo, São Paulo, Brazil

*Imperial College London, South Kensington Campus, London SW7 2AZ, United Kingdom

Publication History

  1. Article first published online: 21 SEP 2012
  2. Manuscript Accepted: 15 AUG 2012
  3. Manuscript Revised: 13 AUG 2012
  4. Manuscript Received: 24 FEB 2012

Funded by

  • NIHR Cardiovascular Biomedical Research Unit at the Royal Brompton and Harefield NHS Foundation Trust and Imperial College London
  • National Institutes of Health. Grant Number: R01HL093038

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Additional Supporting Information may be found in the online version of this article.

FilenameFormatSizeDescription
MRM_24488_sm_SuppFig8.eps404KSupporting Information Figure 8. Modification to the navigator accept/reject algorithm. Only scans within the acceptance window are accepted, but an extra restriction is added that requires the diaphragm position during first and second heartbeats in the STEAM acquisition to be within a 1 mm range.
MRM_24488_sm_SuppFig9.eps171KSupporting Information Figure 9. HA Reproducibility and Comparison of MBH versus NAV in the endocardial layer. Bland-Altman plots and line plots showing the inter-study reproducibility of the MBH and NAV methods. Bland-Altman plot and line plot showing the MBH versus NAV method comparison.
MRM_24488_sm_SuppFig10.eps172KSupporting Information Figure 10. HA Reproducibility and Comparison of MBH versus NAV in the mid-endocardial layer. Bland-Altman plots and line plots showing the inter-study reproducibility of the MBH and NAV methods. Bland-Altman plot and line plot showing the MBH versus NAV method comparison.
MRM_24488_sm_SuppFig11.eps158KSupporting Information Figure 11. HA Reproducibility and Comparison of MBH versus NAV in the mid-epicardial layer. Bland-Altman plots and line plots showing the inter-study reproducibility of the MBH and NAV methods. Bland-Altman plot and line plot showing the MBH versus NAV method comparison.
MRM_24488_sm_SuppFig12.eps164KSupporting Information Figure 12. HA Reproducibility and Comparison of MBH versus NAV in the epicardial layer. Bland-Altman plots and line plots showing the inter-study reproducibility of the MBH and NAV methods. Bland-Altman plot and line plot showing the MBH versus NAV method comparison.

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