Early postsurgical visualization of composite mesh used in ventral hernia repair by amide proton transfer MRI
Article first published online: 19 FEB 2013
Copyright © 2013 Wiley Periodicals, Inc.
Magnetic Resonance in Medicine
Volume 71, Issue 1, pages 313–317, January 2014
How to Cite
Franconi, F., Roux, J., Garric, X. and Lemaire, L. (2014), Early postsurgical visualization of composite mesh used in ventral hernia repair by amide proton transfer MRI. Magn Reson Med, 71: 313–317. doi: 10.1002/mrm.24666
- Issue published online: 17 DEC 2013
- Article first published online: 19 FEB 2013
- Manuscript Accepted: 9 JAN 2013
- Manuscript Revised: 20 DEC 2012
- Manuscript Received: 15 OCT 2012
- magnetic resonance imaging;
- amide proton transfer;
- composite mesh;
- ventral hernia repair;
The feasibility of noninvasive visualization of composite meshes used in ventral hernia repair by amide-proton transfer magnetic resonance imaging (APT-MRI) was explored.
Magnetization transfer asymmetry ratio images of composite meshes were obtained in vitro and in vivo from fast-spin echo acquisitions with frequency saturation offsets of ±3.5 ppm with respect to water frequency and no saturation. Three rats were assessed with APT-MRI each week for 1 month after the intraperitoneal implantation of two meshes, one on each side of the incision. One mesh was coated with collagen and the other was not.
In vitro, meshes were delineated with APT-MRI as a thin continuous linear hypersignal located on one side of the mesh. Unlike collagen-free meshes, collagen-coated meshes were easily identified in vivo with APT-MRI during the first 3 weeks postimplantation. The composite meshes magnetization transfer asymmetry ratio (8.7 ± 2.8%) were significantly different from the muscle magnetization transfer asymmetry ratio value (−0.9 ± 1.6%). After a month, the mesh value dropped down to 1.1 ± 3.9%. Muscle and mesh magnetization transfer asymmetry ratio values were not significantly different and mesh conspicuity was no longer possible.
The results suggest that APT-MRI is a promising technique for noninvasive, early postsurgical visualization of composite meshes used in ventral hernia repair. Magn Reson Med 71:313–317, 2014. © 2013 Wiley Periodicals, Inc.