Spectrally resolved fully phase-encoded three-dimensional fast spin-echo imaging
Article first published online: 11 MAR 2013
Copyright © 2013 Wiley Periodicals, Inc.
Magnetic Resonance in Medicine
Volume 71, Issue 2, pages 681–690, February 2014
How to Cite
Artz, N. S., Hernando, D., Taviani, V., Samsonov, A., Brittain, J. H. and Reeder, S. B. (2014), Spectrally resolved fully phase-encoded three-dimensional fast spin-echo imaging. Magn Reson Med, 71: 681–690. doi: 10.1002/mrm.24704
- Issue published online: 13 JAN 2014
- Article first published online: 11 MAR 2013
- Manuscript Accepted: 4 FEB 2013
- Manuscript Revised: 7 JAN 2013
- Manuscript Received: 21 NOV 2012
- NIH. Grant Numbers: R01 DK083380, R01 DK088925, R01 DK096169, RC1 EB010384, T32 CA009206, R01NS065034
- WARF Accelerator Program
- Research support: GE Healthcare
- fully phase-encoded;
- metal artifact reduction;
- imaging near metal;
- spectroscopic imaging;
- chemical species separation;
- 3D parallel imaging
To develop and test the feasibility of a spectrally resolved fully phase-encoded (SR-FPE) three-dimensional fast spin-echo technique and to demonstrate its application for distortion-free imaging near metal and chemical species separation.
In separate scans at 1.5 T, a hip prosthesis phantom and a sphere filled with gadolinium solution were imaged with SR-FPE and compared to conventional three-dimensional-fast spin-echo. Spectral modeling was performed on the SR-FPE data to generate the following parametric maps: species-specific signal (ρspecies), B0 field inhomogeneity, and R*2. The prosthesis phantom was also scanned using a 16-channel coil at 1.5 T. The fully sampled k-space data were retrospectively undersampled to demonstrate the feasibility of parallel imaging acceleration in all three phase-encoding directions, in combination with corner-cutting and half-Fourier sampling. Finally, SR-FPE was performed with an acetone/water/oil phantom to test chemical species separation.
High quality distortion-free images and parametric maps were generated from SR-FPE. A 4 h SR-FPE scan was retrospectively accelerated to 12 min while preserving spectral information and 7.5 min without preserving spectral data. Chemical species separation was demonstrated in the acetone/water/oil phantom.
This work demonstrates the feasibility of SR-FPE to perform chemical species separation and spectrally resolved imaging near metal without distortion, in scan times appropriate for the clinical setting. Magn Reson Med 71:681–690, 2014. © 2013 Wiley Periodicals, Inc.