Ultra-fast steady state free precession and its application to in vivo 1H morphological and functional lung imaging at 1.5 tesla
Version of Record online: 28 JUN 2013
Copyright © 2013 Wiley Periodicals, Inc.
Magnetic Resonance in Medicine
Volume 70, Issue 3, pages 657–663, September 2013
How to Cite
Bieri, O. (2013), Ultra-fast steady state free precession and its application to in vivo 1H morphological and functional lung imaging at 1.5 tesla. Magn Reson Med, 70: 657–663. doi: 10.1002/mrm.24858
- Issue online: 27 AUG 2013
- Version of Record online: 28 JUN 2013
- Manuscript Accepted: 5 JUN 2013
- Manuscript Revised: 3 JUN 2013
- Manuscript Received: 17 JAN 2013
- Siemens Healthcare
- steady state;
The speed limit for three-dimensional Fourier-encoded steady state free precession (SSFP) imaging is explored on a clinical whole body system and pushed toward a pulse repetition time (TR) close to or even below the 1 ms regime; in the following referred to as ultra-fast SSFP imaging.
To this end, contemporary optimization strategies, such as efficient gradient switching patterns, partial echoes, ramp sampling techniques, and a target-related design of excitation pulses were applied to explore the lower boundaries in TR for SSFP-based Cartesian imaging.
Generally, minimal TR was limited in vivo by peripheral nerve stimulation, allowing a TR ∼1 ms for isotropic resolutions down to about 2 mm. As a result, ultra-fast balanced SSFP provides artifact-free images even for targets with severe susceptibility variations, and native high-resolution structural and functional in vivo 1H imaging of the human lung is demonstrated at 1.5 T.
On clinical whole body MRI systems, the TR of SSFP-based Cartesian imaging can be pushed toward the 1 ms regime. As a result, ultra-fast SSFP protocols might represent a promising new powerful approach for SSFP-based imaging, not only for lung but also in a variety of clinical and scientific applications. Magn Reson Med 70:657–663, 2013. © 2013 Wiley Periodicals, Inc.