Water and fat separation in real-time MRI of joint movement with phase-sensitive bSSFP

Authors

  • Valentina Mazzoli,

    Corresponding author
    1. Biomedical NMR, Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands
    2. Department of Radiology, Academic Medical Center, Amsterdam, The Netherlands
    3. Orthopaedic Research Lab, Radboud University Medical Center, Nijmegen, The Netherlands
    • Correspondence to: Valentina Mazzoli, MSc, Department of Radiology, Academic Medical Center Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands. E-mail: v.mazzoli@amc.uva.nl.

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  • Aart J. Nederveen,

    1. Department of Radiology, Academic Medical Center, Amsterdam, The Netherlands
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  • Jos Oudeman,

    1. Department of Radiology, Academic Medical Center, Amsterdam, The Netherlands
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  • Andre Sprengers,

    1. Orthopaedic Research Lab, Radboud University Medical Center, Nijmegen, The Netherlands
    2. Laboratory of Biomechanical Engineering, University of Twente, Enschede, The Netherlands
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  • Klaas Nicolay,

    1. Biomedical NMR, Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands
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  • Gustav J. Strijkers,

    1. Biomedical NMR, Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands
    2. Biomedical Engineering and Physics, Academic Medical Center, Amsterdam, The Netherlands
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  • Nico Verdonschot

    1. Orthopaedic Research Lab, Radboud University Medical Center, Nijmegen, The Netherlands
    2. Laboratory of Biomechanical Engineering, University of Twente, Enschede, The Netherlands
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  • This work was supported by the “BioMechTools” project, funded by the European Research Council and the European Union COST Action BM1304.

Abstract

Purpose

To introduce a method for obtaining fat-suppressed images in real-time MRI of moving joints at 3 Tesla (T) using a bSSFP sequence with phase detection to enhance visualization of soft tissue structures during motion.

Methods

The wrist and knee of nine volunteers were imaged with a real-time bSSFP sequence while performing dynamic tasks. For appropriate choice of sequence timing parameters, water and fat pixels showed an out-of-phase behavior, which was exploited to reconstruct water and fat images. Additionally, a 2-point Dixon sequence was used for dynamic imaging of the joints, and resulting water and fat images were compared with our proposed method.

Results

The joints could be visualized with good water–fat separation and signal-to-noise ratio (SNR), while maintaining a relatively high temporal resolution (5 fps in knee imaging and 10 fps in wrist imaging). The proposed method produced images of moving joints with higher SNR and higher image quality when compared with the Dixon method.

Conclusions

Water–fat separation is feasible in real-time MRI of moving knee and wrist at 3 T. PS-bSSFP offers movies with higher SNR and higher diagnostic quality when compared with Dixon scans. Magn Reson Med, 2016. © 2016 Wiley Periodicals, Inc.

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