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Keywords:

  • acute motor axonal neuropathy;
  • axonal Guillain–Barré syndrome;
  • axonal regeneration;
  • blood–nerve barrier

Abstract

Patients with acute motor axonal neuropathy (AMAN) generally recover well. We reviewed clinical and electrophysiologic recovery in 13 patients for up to 5 years. Twelve patients showed rapid recovery over 12 months, whereas in the remaining one the recovery was slow and incomplete at 5 years. In AMAN, axonal degeneration appears to develop predominantly in the motor nerve terminals, and only occasionally more proximally in the nerve roots. Nerve terminal degeneration–regeneration presumably provides a mechanism for good recovery. Muscle Nerve, 2007