Case of the Month

Diffuse large B-cell lymphoma presenting as miller fisher syndrome

  1. Nida Usmani MD1,
  2. Rita Bhatia MD2,
  3. Offiong F. Ikpatt MD, PhD3,
  4. Khema R. Sharma MD1,*

Article first published online: 21 DEC 2011

DOI: 10.1002/mus.22223

Issue

Muscle & Nerve

Muscle & Nerve

Volume 45, Issue 1, pages 138–143, January 2012

Additional Information

How to Cite

Usmani, N., Bhatia, R., Ikpatt, O. F. and Sharma, K. R. (2012), Diffuse large B-cell lymphoma presenting as miller fisher syndrome. Muscle Nerve, 45: 138–143. doi: 10.1002/mus.22223

Author Information

  1. 1

    Department of Neurology, Miller School of Medicine (M740), University of Miami, 1150 NW 14th Street, Room 609, Miami, Florida 33136, USA

  2. 2

    Department of Radiology, Miller School of Medicine, University of Miami, Miami, Florida, USA

  3. 3

    Department of Hematopathology, Miller School of Medicine, University of Miami, Miami, Florida, USA

*Department of Neurology, Miller School of Medicine (M740), University of Miami, 1150 NW 14th Street, Room 609, Miami, Florida 33136, USA

Publication History

  1. Issue published online: 21 DEC 2011
  2. Article first published online: 21 DEC 2011
  3. Accepted manuscript online: 8 JUL 2011 07:48AM EST
  4. Manuscript Accepted: 27 JUN 2011

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Keywords:

  • chemotherapy;
  • demyelinating neuropathy;
  • diffuse large B-cell lymphoma;
  • intravenous immunoglobulin;
  • Miller Fisher syndrome

Abstract

We report a patient with diffuse large B-cell lymphoma (DLBCL) who initially presented as Miller Fisher syndrome (MFS) responsive to high-dose immunoglobulin treatment. Detailed investigations for the recurrence of neurological symptoms revealed DLBCL that was responsive to chemotherapy. DLBCL should be considered in the differential diagnosis of patients with MFS who have worsening of their neurological condition after initial improvement with conventional therapy. Muscle Nerve 45: 138–143, 2011

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