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Diffuse large B-cell lymphoma presenting as miller fisher syndrome

Authors

  • Nida Usmani MD,

    1. Department of Neurology, Miller School of Medicine (M740), University of Miami, 1150 NW 14th Street, Room 609, Miami, Florida 33136, USA
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  • Rita Bhatia MD,

    1. Department of Radiology, Miller School of Medicine, University of Miami, Miami, Florida, USA
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  • Offiong F. Ikpatt MD, PhD,

    1. Department of Hematopathology, Miller School of Medicine, University of Miami, Miami, Florida, USA
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  • Khema R. Sharma MD

    Corresponding author
    1. Department of Neurology, Miller School of Medicine (M740), University of Miami, 1150 NW 14th Street, Room 609, Miami, Florida 33136, USA
    • Department of Neurology, Miller School of Medicine (M740), University of Miami, 1150 NW 14th Street, Room 609, Miami, Florida 33136, USA
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Abstract

We report a patient with diffuse large B-cell lymphoma (DLBCL) who initially presented as Miller Fisher syndrome (MFS) responsive to high-dose immunoglobulin treatment. Detailed investigations for the recurrence of neurological symptoms revealed DLBCL that was responsive to chemotherapy. DLBCL should be considered in the differential diagnosis of patients with MFS who have worsening of their neurological condition after initial improvement with conventional therapy. Muscle Nerve 45: 138–143, 2011

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