Oxyneurography: A new technique for the measurement of nerve oxygenation

Authors

  • Joe F. Jabre MD,

    Corresponding author
    1. Department of Neurology, Boston University School of Medicine, 65 Arlington Road, Woburn, Massachusetts 01801, USA
    2. Department of Public Health and Community Medicine, Tufts University School of Medicine, Boston, Massachusetts, USA
    • Department of Neurology, Boston University School of Medicine, 65 Arlington Road, Woburn, Massachusetts 01801, USA
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  • Giovanna M. Squintani MD,

    1. UO Neurologia, Azienda Ospedaliera Universitaria Integrata, Verona, Italy
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  • Kenneth K.H. Chui PhD

    1. Department of Public Health and Community Medicine, Tufts University School of Medicine, Boston, Massachusetts, USA
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Abstract

Introduction:

Near-infrared spectroscopy (NIRS) is a non-invasive technique used to measure tissue oxygenation. In this study we describe oxyneurography (ONG), a novel application of the NIRS technique in non-invasive surface measurement of oxygenation in ulnar nerve.

Methods:

NIRS sensors were applied directly over the ulnar epicondylar groove to measure the ulnar nerve ONG index, a ratio of oxygenated over total hemoglobin content. Ulnar motor conduction studies were obtained in all subjects.

Results:

The ONG index and ulnar motor conduction had a positive linear association. Ulnar motor conduction could be linearly predicted by the ONG index. The ONG index showed a sensitivity of 1.0 and a specificity of 0.852 for the presence of an ulnar neuropathy symptom. During limb ischemia, the ONG index gradually decreased.

Conclusions:

Oxyneurography can lead to the early detection of a compromise in a nerve's oxygenation status leading to neuropathy. Muscle Nerve 45:75–80, 2012

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