The assisted 6-minute cycling test to assess endurance in children with a neuromuscular disorder

Authors

  • Merel Jansen PT, MSc,

    Corresponding author
    1. Department of Rehabilitation, Nijmegen Centre for Evidence Based Practice, Radboud University Nijmegen Medical Centre, Reinier Postlaan 4, 6525 GC Nijmegen, The Netherlands
    • Department of Rehabilitation, Nijmegen Centre for Evidence Based Practice, Radboud University Nijmegen Medical Centre, Reinier Postlaan 4, 6525 GC Nijmegen, The Netherlands
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  • Moniek De Jong MS,

    1. Department of Rehabilitation, Nijmegen Centre for Evidence Based Practice, Radboud University Nijmegen Medical Centre, Reinier Postlaan 4, 6525 GC Nijmegen, The Netherlands
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  • Hanna M. Coes MS,

    1. Department of Rehabilitation, Nijmegen Centre for Evidence Based Practice, Radboud University Nijmegen Medical Centre, Reinier Postlaan 4, 6525 GC Nijmegen, The Netherlands
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  • Florieke Eggermont MS,

    1. Department of Rehabilitation, Nijmegen Centre for Evidence Based Practice, Radboud University Nijmegen Medical Centre, Reinier Postlaan 4, 6525 GC Nijmegen, The Netherlands
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  • Nens Van Alfen MD, PhD,

    1. Department of Neurology and Clinical Neurophysiology, Donders Centre for Neuroscience, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
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  • Imelda J.M. De Groot MD, PhD

    1. Department of Rehabilitation, Nijmegen Centre for Evidence Based Practice, Radboud University Nijmegen Medical Centre, Reinier Postlaan 4, 6525 GC Nijmegen, The Netherlands
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Abstract

Introduction: For late- or non-ambulant children with a neuromuscular disorder no suitable endurance tests are currently available. We developed the assisted 6-minute cycling test (A6MCT) for the legs and arms and investigated its psychometric properties in healthy boys and boys with Duchenne muscular dystrophy (DMD). Methods: Ninety-nine healthy boys and 30 boys with DMD (12 wheelchair-dependent) performed the A6MCT. Seventy healthy boys also performed the 6-minute walk test (6MWT), and 23 boys performed the A6MCT twice within 2 weeks. Boys with DMD also performed the Motor Function Measure (MFM). Results: The A6MCT was feasible for >90% of all boys. Boys with DMD achieved fewer cycling revolutions than controls. The A6MCT was positively correlated with the 6MWT and was reproducible in healthy boys, and it correlated with disease severity in boys with DMD. Conclusions: The A6MCT is a promising outcome measure for the follow-up of non-ambulant children with a neuromuscular disorder. Muscle Nerve 46: 520–530, 2012

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