A more detailed mechanism to explain the “bands of Fontana” in peripheral nerves
Article first published online: 13 SEP 2012
Copyright © 2012 Wiley Periodicals, Inc.
Muscle & Nerve
Volume 46, Issue 4, pages 540–547, October 2012
How to Cite
Merolli, A., Mingarelli, L. and Rocchi, L. (2012), A more detailed mechanism to explain the “bands of Fontana” in peripheral nerves. Muscle Nerve, 46: 540–547. doi: 10.1002/mus.23422
- Issue published online: 13 SEP 2012
- Article first published online: 13 SEP 2012
- Accepted manuscript online: 24 APR 2012 05:48AM EST
- Manuscript Accepted: 10 APR 2012
- computer-assisted design;
- in vivo;
- nerve guide;
- operative microscope;
- peripheral nerve
In 1779, Fontana identified transverse and oblique bands along peripheral nerves. Subsequent studies pointed alternatively to endoneural or perineural components as the cause. Our aim was to clarify these conflicting findings.
Recoiling of the bands of Fontana was video-recorded in the rat sciatic nerve. Computer-assisted design (CAD) software was used to model the nerve by interference figures.
In vivo microdissection showed distinctive, black-and-white, closely packed bands in the perineurium, which differed from the widely spaced, translucent, dark/pale gray, staggered bands in the endoneurium. CAD merging of these 2 patterns produced images resembling the bands observed in vivo.
Two repetitive structures with different characteristics, 1 in the perineurium and the other in the endoneurium, merge to give the appearance of these bands. Muscle Nerve 46: 540–547, 2012